The song, penned by DOE along with Jonathan McReynolds, Rickey Slikk Muzik Offord, Juan Winans, Kelby Shavon Johnson, Jr., Jesse Paul Barrera, Jeffrey Castro Bernat, and Timothy Ferguson, is a self declaration of self empowerment. "Holy Hands" reminds listeners that they are good enough in the eyes and heart of God.
In her illustrious career to date, DOE has achieved three No. 1 singles ("Brighter," "When I Pray," and "Cuán Bueno"). She has performed at the Stellar Awards, Gospel Super Fest, and the GMA Dove Awards, and to date, her music has received 36+ million streams. "Lead Us Again" is the first to release from her forthcoming sophomore album, slated to release this fall. The album follows her debut, 2022's Clarity. DOE is currently touring on the McDonald's Inspiration Celebration Gospel Tour.